European Medicines Company probes whether or not weight reduction jabs similar to Ozempic enhance danger of uncommon sort of blindness – CSN Information

The European Medicines Company (EMA) has launched an investigation into whether or not weight reduction jabs similar to Ozempic trigger blindness. The Pharmacovigilance Threat Evaluation Committee (PRAC) of the EMA is reviewing medicines containing semaglutide following issues about an elevated danger of creating Naion, a uncommon eye situation, which was instructed by two current research.

Semaglutide is the lively ingredient in quite a few medicines used within the remedy of diabetes and weight problems, similar to Ozempic, Rybelsus and Wegovy.

The PRAC is at present assessing whether or not sufferers handled with semaglutide could also be at elevated danger of creating Naion. It is a situation brought on by lowered blood circulate to the optic nerve of the attention that may result in lack of imaginative and prescient. Sufferers with sort 2 diabetes might have already got an inherently larger danger of creating the situation, the EMA identified.

One of many research suggesting an elevated danger was revealed within the worldwide journal of retina and vitreous. Danish researchers checked out all folks with sort 2 diabetes within the nation for 5 years and concluded that utilizing semaglutide as soon as per week independently doubled the chance of Naion.

“Given the irreversible nature of Naion, it is very important recognise this danger, and future research ought to search to determine high-risk subgroups,” the researchers mentioned,

Different hostile results

This uncommon blindness is just not the one hostile impact related to the brand new technology of miracle medicine. Giant-scale analysis revealed this summer time on the College of British Columbia College of Drugs identified that their use is related to an elevated danger of “probably severe” gastrointestinal situations, similar to abdomen paralysis, pancreatitis and intestinal obstruction.

Some analysis has discovered a hyperlink with elevated suicidal ideas. Work by the Northwell Well being medical centre in New York and the College of Zurich discovered that taking semaglutide will increase suicidal ideation “disproportionately”. This impact was solely seen in remedy for despair or anxiousness.

Taking these medicine might additionally have an effect on youngsters’s improvement, in keeping with analysis. Specialists on the College of California discovered that whereas Ozempic might assist morbidly overweight youngsters, in different younger folks it reduces the calorie consumption wanted for train, development and improvement.