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Grace Davidson and baby Amy with the Queen Charlotte’s and Chelsea Hospital team in London celebrating the UK’s First Birth following a Womb Transplant.
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A British woman has given birth to a healthy baby girl following a uterus transplant from her sister — a first in the UK and a powerful breakthrough in fertility and reproductive medicine.
Grace Davidson, a 36-year-old woman who was born with no uterus because of a rare congenital disorder, gave birth on 27th February 2025 to Amy Isabel at Queen Charlotte’s and Chelsea Hospital, London. Two years ago, Grace Davidson, 36, who was born without a uterus due to a rare congenital condition, gave birth to Amy Isabel at Queen Charlotte’s and Chelsea Hospital in London.
Grace said that the moment when she held her child was “the most beautiful gift we could hope for.”
Fertility breakthrough from a rare uterine disorder
Grace was diagnosed as a teenager with MRKH, a rare disorder that affects 1 in 5,000 woman. The uterus is either underdeveloped or absent. While her ovaries remained functional, she was told she would never carry a child — until now.
The complex surgery was performed in February 2023 by a team of surgeons led by Isabel Quiroga, Richard Smith and the Oxford Transplant Centre. After months of recuperation and immunosuppressive treatment to prevent rejection, a created embryo via IVF implanted.
The little girl’s name, Amy Isabel, pays tribute not only to her aunt — the organ donor — but also to the surgeon who made the procedure possible.
The future of fertility is being shaped by groundbreaking womb-transplantation techniques
Since the first successful procedure performed in Sweden in 2013, more than 100 uterus implants have been performed worldwide. Since 2013, 50 babies were born as a result of the groundbreaking surgery. This gives hope to women who had been told that they would never be able to conceive.
Professor Richard Smith said, “This is pure joy.” He has worked on the UK’s Living Donor Transplant Programme for over 25 years. “We have finally had a baby in Britain born through this extraordinary technique.”
Grace and her spouse hope that their story inspires more research and greater access to this treatment. This could transform the lives of future generations.
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